Tricyclic antidepressants can induce mild myoclonus. As this may be a sign of toxicity, the blood level may be checked (if available) to ensure that it is not excessive. If the myoclonus is symptomatic and the blood level is within the recommended range, the patient may be treated with clonazepam at a dose of 0.25 mg t.i.d.
Ref: - American Psychiatric Association treatment recommendations for patients with major depressive disorder (second edition)
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This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
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This blog is only for educational purpose of psychiatrists and other physicians. The information published in this blog is not intended for use as a substitute for consultation to a licensed health professional. Patients and consumers who visit Psychopharmacology Tips should carefully review the information gathered from the site with a professional healthcare provider.