If depression is associated with the prodrome or onset of a psychotic episode, antipsychotic medication is usually the most effective treatment for both the depression and the psychotic episode. However, when depression occurs in the context of relative remission of psychosis, antidepressant medication can be useful.
Ref: - Siris, S.G., Morgan, V., Fagerstrom, R., et al. (1987) Adjunctive imipramine in the treatment of postpsychotic depression: a controlled trial. Archives of General Psychiatry, 44: 533-539.
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This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
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This blog is only for educational purpose of psychiatrists and other physicians. The information published in this blog is not intended for use as a substitute for consultation to a licensed health professional. Patients and consumers who visit Psychopharmacology Tips should carefully review the information gathered from the site with a professional healthcare provider.