Psychopharmacology Tips
Roughening in depression and bipolar disorder
12/07/04
Roughening in depression and bipolar disorder
Many patients suffering from affective disorders may intermittently experience symptoms during the continuation phase of their treatment, and this phenomenon has been called “roughening”. Roughening with features of depression often resolves without intervention. However, roughening with symptoms of mood elevation in bipolar patients should be monitored more closely, because this type of symptom recurrence appears more likely to develop into a full affective episode.
Ref: - Rosenbaum, J.F., Fava, M., Nierenberg, A.A. & Sachs, G.S. (1999) Treatment-resistant mood disorders. In: Treatment of Psychiatric Disorders. (Ed) Gabbard, G.O. pp 1275 – 1328. New Delhi: Jaypee Brothers
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Psychopharmacology Tips
This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
Psychopharmacology Tips is a part of PsyPlexus, a portal for mental health professionals.
This blog is only for educational purpose of psychiatrists and other physicians. The information published in this blog is not intended for use as a substitute for consultation to a licensed health professional. Patients and consumers who visit Psychopharmacology Tips should carefully review the information gathered from the site with a professional healthcare provider.
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