Jaundice has been noted to occur in 0.1%-0.5% of patients taking chlorpromazine. This usually occurs within the first month after the initiation of treatment and generally requires discontinuation of treatment. Given the relative infrequency of antipsychotic-induced jaundice, other etiologies for jaundice should be evaluated before the cause is judged to be the antipsychotic medication.
Ref: - American Psychiatric Association practice guideline for the treatment of patients with schizophrenia (first edition)
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This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
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