Risperidone and Quetiapine: Food and smoking do not modify the pharmacokinetics
Olanzapine: Bioavailability unaffected by food; smoking can reduce its half life
Clozapine: Bioavailability not affected by food; half life could be reduced by smoking
Ref: - Tandon, R., Milner, K. & Jibson, M.D. (1999) Antipsychotics from theory to practice: integrating clinical and basic data. Journal of Clinical Psychiatry, 60 (suppl 8): 21-28.
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This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
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