Psychopharmacology Tips
Lithium: delay in onset of action
12/19/04
Lithium: delay in onset of action
Though the antimanic effect of lithium occurs within 6-10 days, there is a delay of 6-8 weeks in onset of its antidepressant effect.
References: -
Franchini L., Zanardi, R., Gasperini, M., et al. (1996) Fluvoxamine and lithium in long term treatment of unipolar subjects with high recurrence rate. Journal of Affective Disorders, 38: 67-69.
Zornberg, G.L. & Pope H.G. Jr. (1993) Treatment of depression in bipolar disorder: new directions for research. Journal of Clinical Psychopharmacology, 13: 397-408.
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Psychopharmacology Tips
This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
Psychopharmacology Tips is a part of PsyPlexus, a portal for mental health professionals.
This blog is only for educational purpose of psychiatrists and other physicians. The information published in this blog is not intended for use as a substitute for consultation to a licensed health professional. Patients and consumers who visit Psychopharmacology Tips should carefully review the information gathered from the site with a professional healthcare provider.
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