Psychopharmacology Tips
Tackling non-response to few weeks of fluoxetine
01/26/05
Tackling non-response to few weeks of fluoxetine
07:08:00 pm, Categories: Antidepressants Schweizer et al. (1990) has shown that there was no significant difference in response rates if non-responders to fluoxetine at three weeks were randomized to either fluoxetine 20 mg/day or 60 mg/day for a further 5 weeks. This indicates that, at least in the first 8 weeks of treatment with fluoxetine, ‘tincture of time’ may be more important than dosage increase.
Ref: - Schweizer, E., Rickels, K., Amsterdam, J.D., et al. (1990) What constitutes an adequate antidepressant trial of fluoxetine? Journal of Clinical Psychiatry, 51, 8-11.
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Psychopharmacology Tips
This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
Psychopharmacology Tips is a part of PsyPlexus, a portal for mental health professionals.
This blog is only for educational purpose of psychiatrists and other physicians. The information published in this blog is not intended for use as a substitute for consultation to a licensed health professional. Patients and consumers who visit Psychopharmacology Tips should carefully review the information gathered from the site with a professional healthcare provider.
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