A prospective study of depressed patients found that panic attacks are correlated with a poor outcome (Coryell et al., 1988). There is some evidence that such patients may do better with MAOIs (O’Reardon and Amsterdam, 2001)
Ref: -
Coryell, W., Endicott, J., Andreasen, N.C., et al. (1988) Depression and panic attacks: the significance as reflected in follow-up and family study data. American Journal of Psychiatry, 145, 293-300.
O’Reardon, J.P. & Amsterdam, J.D. (2001) Overview of treatment-resistant depression and its management. In: Treatment-resistant mood disorders, (Eds.) Amsterdam, J.D., Hornig, M. & Nierenberg, A.A. pp 30 – 45, Cambridge: Cambridge University Press.
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This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
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