Psychopharmacology Tips

Memory impairment in the Korsakoff syndrome has shown mild response to treatment with clonidine, methysergide, and methylphenidate (McEntee and Crook, 1990), while physostigmine has been found useful in cases with amnestic disorder due to herpes simplex encephalitis (Catsman-Berrevoets et al., 1986, Peters and Levin, 1977).

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Catsman-Berrevoets, C.E., Van Harskamp, F. & Applehof, A. (1986) Beneficial effect of physostigmine on clinical amnesic behavior and neuropsychological test results in a patient with a post-encephalitic amnesic syndrome. Journal of Neurology Neurosurgery and Psychiatry, 49, 1088-1090.

McEntee, W.J & Crook, TH. (1990) Age-associated memory impairment: a role for catecholamines. Neurology, 40, 526-530.

Peters, B.H. & Levin, H.S. (1977) Memory enhancement after physostigmine treatment in the amnesic syndrome. Archives of Neurology, 34, 215-219.