Episodic nausea occurring only after each dose may be due to local gastric irritation and may be relieved by talking lithium with food. Clinically, any side effect that mainly occurs 1-2 hours after each oral dose of the standard preparation of lithium might be improved by changing to the sustained-release form.
Ref: - Schatzberg, A.F., Cole, J.O. & DeBattista, C. (2003) Manual of Clinical Psychopharmacology. Washington, DC: American Psychiatric Press.
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This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
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