A new emergence of depression in a patient with a history of schizophrenia might be a harbinger of the emergence of a new episode psychosis, generally within a week or two. An appropriate treatment response for a new episode of depression in such a patient, therefore, is increased surveillance (especially with regard to psychotic or disinhibited behaviour), ensuring adherence with antipsychotic medication regimens, interventions to reduce stress, and the bolstering of nonspecific psychosocial supports (Siris, 2005).
Ref: - Sirius, S.G. (2005) Managing depression in schizophrenia. Psychiatric Annals, 35, 1, 61- 69.
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This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
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