Pretreatment with an antidepressant such as paroxetine starting two weeks before the interferon therapy can reduce depression induced by interferon alpha (Musselman et al., 2001).
Ref: - Musselman, D.L., Lawson, D.H., Gumnick, J,F, et al. (2001) Paroxetine for prevention of depression induced by high-dose interferon alpha. New England Journal of Medicine, 344, 13, 961-966.
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This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
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