Psychopharmacology Tips
Clinical features of clozapine-induced neuroleptic malignant syndrome
05/01/05
Clinical features of clozapine-induced neuroleptic malignant syndrome
10:20:31 am, Categories: Antipsychotics Neuroleptic malignant syndrome associated with clozapine may be atypical and tend not to be characterized by rigidity, fevers, and elevation of creatine phosphokinase that are seen with standard antipsychotic drugs. Rather, the presentation in clozapine-treated patients may include delirium, autonomic instability, and milder extrapyramidal symptoms (Hasan and Buckley, 1998; Karagianis et al., 1999).
Ref:-
Hasan, S. & Buckley, P. (1998) Novel antipsychotics and the neuroleptic malignant syndrome: a review and critique. American Journal of Psychiatry, 155, 1113-1116.
Karagianis, J.L., Philips, L.C., Hogan, K.P., et al. (1999) Clozapine-associated neuroleptic syndrome: two new cases and a review of the literature. Annals of Pharmacotherapy, 33, 623-630.
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Psychopharmacology Tips
This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
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