After a detailed review of the literature, Allen and Hollander (2000) concludes that SSRIs are the first-line therapy for body dysmorphic disorder, with the dosage and length of trial similar to those used for OCD. In refractory cases, especially if delusional conviction is present, augmentation with low doses of atypical antipsychotics might be effective. Other augmentation strategies that are clinically used include adding bupropion, gabapentin, or stimulants such as dexamphetamine to the SSRI therapy.
Ref: - Allen, A. & Hollander, E. (2000) Body dysmorphic disorder. The Psychiatric Clinics of North America, 23 (3), 617 – 628.
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This blog on Clinical Psychopharmacology is maintained by Dr. Shahul Ameen, M.D., Psychiatrist, St. John's Hospital, Kattappana, Idukki, Kerala, India.
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